ToeFX is a photodisinfection therapy designed to eliminate even
the severest fungal infections.

Using the synergistic power of light and oxygen, ToeFX disrupts fungal cells at their source - safely, painlessly, and without the side effects of traditional treatments.

Safe

No side-effects

PAINLESS

No intense heat

Non-Invasive

Non-toxic

The Power of ToeFX Therapy Light

The light source transfers energy to the affected area of the nail, disrupting fungal structures at the cellular level. When used with the ToeFX topical formulation, which helps visualize the treatment area, the system delivers a precise, light-activated approach to managing nail health - all without drugs, discomfort, or downtime.
The ToeFX TFX1000N is designed to deliver consistent, clinically optimized red light exposure to affected nails. Its single-spectrum architecture ensures precise energy delivery - uniform, predictable, and finely controlled. Developed through photomedicine research, the TFX1000N provides reliable light distribution that supports localized tissue health and natural nail renewal. Ideal for clinics seeking a dependable, high-performance phototherapy platform.
The ToeFX LT2000 integrates dual-band visible light technology designed to deliver complementary biological effects within the nail and periungual tissues. The system’s precisely calibrated spectral output ensures uniform light distribution and reproducible fluence across the treatment field. This harmonized approach enables broad-spectrum microbial disruption and supports endogenous tissue renewal processes - without heat, discomfort, or pharmacological agents.

Mode of Action

The ToeFX formulation facilitates visualization of the affected nail surface and enhances the precision of light delivery. When exposed to red light, short-lived reactive oxygen species (ROS) are generated at the illuminated interface. These ROS participate in controlled, localized photochemical reactions that dissipate immediately once the light source is removed – ensuring a self-limiting and well-tolerated procedure.

Scientifically Proven Results

Landmark 18 months longitudinal clinical study involving 165 nails, focused on severe cases: totally dystrophic nails and dermatophytomas.
Accepted for publication with JAPMA.

Study Aim

Evaluate the safety and efficacy of a novel light therapy for severe onychomycosis, including totally dystrophic nails. Included “non-model” patients with co-morbidities, who are often excluded.

Patient Characteristics

  • 165 nails
  • Average age: 60 years
  • 80% of patients had infections for 5 years or more
  • Three centres, several providers, same protocol
  • Diagnosis confirmed through KOH, culture, and/or PCR
  • Comorbidities allowed – heart disease, tinea pedis, psoriasis, cardiovascular issues

ToeFX Success

  •  73% success rate, defined as total clearance or ≥3mm of healthy new nail growth
  • 58% (of available data) achieved mycological cure
  • High patient satisfaction
  • Rapid visual improvement, often within weeks

Clinically Proven Results

The ToeFX study has been accepted for publication by the Journal of the American Podiatric Medical Association (JAPMA) - offering peer-reviewed validation as a reliable and effective treatment for onychomycosis.

No Drugs. No Pain.
Only Real Results.

Whether used on its own or in combination with other treatment plans, ToeFX is a new standard in fungal nail care, one that is patient-friendly, science-backed, and revenue-generating for clinics.
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73%

efficacy

100%

selective

5 mins

clinician time

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